Based on a true story of rags to riches to redemption, Margaret grows up on a farm in thirteenth century Tuscany and blossoms into a beautiful teenager. She runs away with Arsenio, a handsome nobleman. When Arsenio is murdered, Margaret is cast out by his family and then by her cruel stepmother. She is taken in by a kindly friar and experiences religious visions. She becomes a nun, nurses the sick, and assists with an exorcism. Margaret goes on to establish a hospital and miracles are attributed to her. Margaret becomes a saint whose body remains incorruptible.