Plasmatics is an inner-city blood plasma donation center that hosts a diverse, multi-generational band of donors who exchange plasma for money. The center is the life’s work of Darla, a self-made businesswoman who has long treated the donors at her facility like a family, but after a business deal gone wrong, the means of survival are threatened for donors and staff alike. The intelligent, but domineering Sandridge, wise and kind Mr. Bobby, earthy Lindy, conservative Kinnon, observant Ros, and more, are left to define family, expose the boundaries of capitalism, trust, and racial inequity as they wrestle with haunting pasts, the hard-scrabble present, and uncertain futures.